Wednesday, October 6, 2010

NYT: Rampant Fraud Threat to China's Brisk Ascent

Today, New York Times pays attention to China's credibility problems and Fang Zhuozi's efforts in exposing them:

Rampant Fraud Threat to China's Brisk Ascent
Andrew Jacobs

BEIJING — No one disputes Zhang Wuben’s talents as a salesman. Through television shows, DVDs and a best-selling book, he convinced millions of people that raw eggplant and immense quantities of mung beans could cure lupus, diabetes, depression and cancer.

For $450, seriously ill patients could buy a 10-minute consultation and a prescription — except Mr. Zhang, one of the most popular practitioners of traditional Chinese medicine, was booked through 2012.

But when the price of mung beans skyrocketed this spring, Chinese journalists began digging deeper. They learned that contrary to his claims, Mr. Zhang, 47, was not from a long line of doctors (his father was a weaver). Nor did he earn a degree from Beijing Medical University (his only formal education, it turned out, was the brief correspondence course he took after losing his job at a textile mill).

The exposure of Mr. Zheng’s faked credentials provoked a fresh round of hand-wringing over what many scholars and Chinese complain are the dishonest practices that permeate society, including students who cheat on college entrance exams, scholars who promote fake or unoriginal research, and dairy companies that sell poisoned milk to infants.

The most recent string of revelations has been bracing. After a plane crash in August killed 42 people in northeast China, officials discovered that 100 pilots who worked for the airline’s parent company had falsified their flying histories. Then there was the padded resume of Tang Jun, the millionaire former head of Microsoft China and something of a national hero, who falsely claimed to have received a doctorate from the California Institute of Technology.

Few countries are immune to high profile frauds. Illegal doping in sports and malfeasance on Wall Street are running scandals in the United States. But in China, fakery in one area in particular — education and scientific research — is pervasive enough that many here worry it could make it harder for the country to climb the next rung on the economic ladder.

A Lack of Integrity

China devotes significant resources to building a world-class education system and pioneering research in competitive industries and sciences, and has had notable successes in network computing, clean energy, and military technology. But a lack of integrity among researchers is hindering China’s potential and harming collaboration between Chinese scholars and their international counterparts, scholars in China and abroad say.

“If we don’t change our ways, we will be excluded from the global academic community,” said Zhang Ming, a professor of International Relations at Renmin University in Beijing. “We need to focus on seeking truth, not serving the agenda of some bureaucrat or satisfying the desire for personal profit.”

Pressure on scholars by administrators of state-run universities to earn journal citations — a measure of innovation — has produced a deluge of plagiarized or fabricated research. Last December, a British journal that specializes in crystal formations announced that it was withdrawing more than 70 papers by Chinese authors whose research was of questionable originality or rigor.

In an editorial published earlier this year, The Lancet, the British medical journal, warned that faked or plagiarized research posed a threat to President Hu Jintao’s vow to make China a “research superpower” by 2020.

“Clearly, China’s government needs to take this episode as a cue to reinvigorate standards for teaching research ethics and for the conduct of the research itself,” the editorial said. Last month a collection of scientific journals published by Zhejiang University in Hangzhou reignited the firestorm by publicizing results from a 20-month experiment with software that detects plagiarism. The software, called CrossCheck, rejected nearly a third of all submissions on suspicion that the content was pirated from previously published research. In some cases, more than 80 percent of a paper’s content was deemed unoriginal.

The journals’ editor, Zhang Yuehong, emphasized that not all the flawed papers originated in China, although she declined to reveal the breakdown of submissions. “Some were from South Korea, India and Iran,” she said.

The journals, which specialize in medicine, physics, engineering and computer science, were the first in China to use the software. For the moment they are the only ones to do so, Ms. Zhang said.

Plagiarism and Fakery

Her findings are not surprising if one considers the results of a recent government study in which a third of the 6,000 scientists at six of the nation’s top institutions admitted they had engaged in plagiarism or the outright fabrication of research data. In another study of 32,000 scientists last summer by the China Association for Science and Technology, over 55 percent said they knew someone guilty of academic fraud.

Fang Shimin, a muckraking writer who has become a well-known advocate for academic integrity, said the problem started with the state-run university system, where politically appointed bureaucrats have little expertise in the fields they oversee. Because competition for grants, housing perks and career advancement is so intense, officials base their decisions on the number of papers published.

“Even fake papers count because nobody actually reads them,” said Mr. Fang, who is more widely known by his pen name, Fang Zhouzi, and whose Web site, New Threads, has exposed more than 900 instances of fakery, some involving university presidents and nationally lionized researchers.

When plagiarism is exposed, colleagues and school leaders often close ranks around the accused. Mr. Fang said this was partly because preserving relationships trumped protecting the reputation of the institution. But the other reason, he said, is more sobering: few academics are clean enough to point a finger at others. The result is that plagiarizers often go unpunished, which only encourages more of it, said Zeng Guoping, director of the Institute of Science Technology and Society at Tsinghua University in Beijing, which helped run the survey of 6,000 academics.

He cited the case of Chen Jin, a computer scientist who was once celebrated for having invented a sophisticated microprocessor but who, it turned out, had taken a chip made by Motorola, scratched out its name, and claimed it as his own. Showered with government largesse and accolades, the exposure in 2006 was an embarrassment for the scientific establishment that backed him.

But even though Mr. Chen lost his university post, he was never prosecuted. “When people see the accused still driving their flashy cars, it sends the wrong message,” Mr. Zeng said.

The problem is not confined to the realm of science. In fact many educators say the culture of cheating takes root in high school, where the competition for slots in the country’s best colleges is unrelenting and high marks on standardized tests are the most important criterion for admission. Ghost-written essays and test questions can be bought. So, too, can a “hired gun” test taker who will assume the student’s identity for the grueling two-day college entrance exam.

Then there are the gadgets — wristwatches and pens embedded with tiny cameras — that transmit signals to collaborators on the outside who then relay back the correct answers. Even if such products are illegal, students spent $150 million last year on Internet essays and high-tech subterfuge, a five-fold increase over 2007, according to a Wuhan University study, which identified 800 Web sites offering such illicit services.

Academic deceit is not limited to high school students. In July, Centenary College, a New Jersey institution with satellite branches in China and Taiwan, shuttered its business schools in Shanghai, Beijing and Taipei after finding rampant cheating among students. Although school administrators declined to discuss the nature of the misconduct, it was serious enough to withhold degrees from each of the programs’ 400 students. Given a chance to receive their M.B.A.’s by taking another exam, all but two declined, school officials said.

Nonchalant Cheating

Ask any Chinese student about academic skullduggery and the response is startlingly nonchalant. Lu Xiaoda, an engineering student who last spring graduated from Tsinghua University, considered a plum of the country’s college system, said it was common for students to swap test answers or plagiarize essays from one another. “Perhaps it’s a cultural difference but there is nothing bad or embarrassing about it,” said Mr. Lu, who this semester started on a master’s degree at Stanford University. “It’s not that students can’t do the work. They just see it as a way of saving time.”

The Chinese government has vowed to address the problem. Editorials in the state-run press frequently condemn plagiarism and last month, Liu Dongdong, a powerful Politburo member who oversees Chinese publications, vowed to close some of the 5,000 academic journals whose sole existence, many scholars say, is to provide an outlet for doctoral students and professors eager to inflate their publishing credentials.

Fang Shimin and another crusading journalist, Fang Xuanchang, have heard the vows and threats before. In 2004 and again in 2006, the Ministry of Education announced antifraud campaigns but the two bodies they established to tackle the problem have yet to mete out any punishments.

In recent years, both journalists have taken on Xiao Chuanguo, a urologist who invented a surgical procedure aimed at restoring bladder function in children with spina bifida, a congenital deformation of the spinal column that can lead to incontinence, and when untreated, kidney failure and death.

In a series of investigative articles and blog postings, the two men uncovered discrepancies in Dr. Xiao’s Web site, including claims that he had published 26 articles in English-language journals (they could only find four) and that he had won an achievement award from the American Urological Association (the award was for an essay he wrote).

But even more troubling, they said, were assertions that his surgery had an 85 percent success rate. Of more than 100 patients interviewed, they said none reported having been cured of incontinence, with nearly 40 percent saying their health had worsened after the procedure, which involved rerouting a leg nerve to the bladder. Wherever the truth may have been, Dr. Xiao was incensed. He filed a string of libel suits against Fang Shimin and told anyone who would listen that revenge would be his.

This summer both men were brutally attacked on the street in Beijing — Fang Xuanchang by thugs with an iron bar and Fang Shimin by two men wielding pepper spray and a hammer.

When the police arrested Dr. Xiao on Sept. 21, he quickly confessed to hiring the men to carry out the attack, according to the police report. His reason, he said, was vengeance for the revelations he blames for blocking his appointment to the prestigious Chinese Academy of Social Sciences.

Despite his confession, Dr. Xiao’s employer, Huazhong University of Science and Technology, appeared unwilling to take any action against him. In the statement they released, administrators said they were shocked by news of his arrest but said they would await the outcome of judicial procedures before severing their ties to him.

Thursday, September 30, 2010

International Scholars Issue Open Letter Supporting Xiao Chuanguo

Exactly one year ago, Hollywood celebrities were busy writing appealing letters on behalf of Roman Polanski, a movie director who was convicted for child rape. A couple of years earlier, a world-renowned scientist, William French Anderson, might have his sentence for molestation reduced because of supporting letters from his colleagues, including a Nobel Laureate.

Today, 31 internationally-renowned scholars, most of whom are accepting fundings for experiments on Xiao's Procedure, issued an open letter supporting Dr. Xiao Chuanguo, who had confessed to the hideous crime of masterminding two brutal attacks on an investigative reporter and a free-lance writer who had worked to expose his fraud.

The common thread of these letters is that their authors pay little or no regards to the horrible injuries caused by the perpetrators, in the name that the criminals or suspects had previous made valuable contributions to the society and therefore somehow should be judged more than mere citizens. Where are the moral standards?

In addition, this particular letter once again states the Beaumont Hospital result has confirmed that "[nerve] rerouting does occur," without even a mention of the critical comments by their peers published in the same issue of the Journal of Urology. Where is scholastic honesty?

To those protected elites who never fail to protect one of their own, where is the shame?

Below is the open letter, in its entire glory:

Open letter in support of Chuan-Guo Xiao, M.D. from the
International Academic Community

September 29, 2010

To all,

We have all had the pleasure of knowing Dr. Chuan-Guo Xiao for many years. He is an internationally respected surgeon-scientist who has made major advances in the development of neuroregeneration to restore voiding and bowel function. Dr. Xiao performed groundbreaking animal research in the United States, demonstrating that a motor nerve that innervates the leg can be used to reinnervate the bladder and bowel. This reinnervation allows for development of a reflex to initiate bladder function. The results of his studies were published in peer-reviewed journals and other scientists have replicated Xiao’s findings confirming these results.

Dr. Xiao eventually took the courageous step of moving from animal research to human studies and began performing the rerouting procedure on patients with spinal cord injury and spina bifida in China. Neurogenic bladder is life threatening in China due to a lack of both antimuscarinics and intermittent catheterization, and lessening the complications of neurogenic bladder would be considered a lifesaving success. Patients with neurogenic bladder and bowel suffer greatly and endure a host of issues such as urinary retention, incontinence, recurrent infections, renal insufficiency, fecal incontinence, constipation, and poor quality of life. For a procedure as complicated as nerve rerouting requiring nerve regeneration, one cannot expect normalization of bladder and bowel function to be the definition of success. What is important is that the benefits outweigh the risks of the procedure.

Dr. Xiao published his clinical results in peer-reviewed journals and was twice honored by the Jack Lapides Essay Contest, one of the most respected international awards given to scientists who make major contributions to the field of neurourology. In 2008, he was named the Kelm Hjalmas Memorial Lecturer from the International Children’s Continence Society for his scientific achievements. Many of us have traveled to China to examine patients treated by Dr. Xiao and/or have been trained by him in the nerve rerouting surgery he invented. Dr. Xiao is a very skilled surgeon who is passionate about patient care and works tirelessly to train physicians around the world in performing his nerve rerouting procedure.

In the United States, an independent and very rigorous pilot research trial was performed to test the safety and efficacy of this procedure. The one-year results were recently published in the Journal of Urology. At the 12-month follow-up visit, a cutaneous to bladder reflex was found in 7 of 9 spina bifida patients, confirming that rerouting does occur. This finding by itself is remarkable and Dr. Xiao should be commended. In addition, a number of patients demonstrated improvement in bladder and bowel function, which has continued to improve with longer patient follow-up.

The 36-month results are currently being analyzed and will be reported in the near future. The pilot data was supportive of Dr. Xiao’s procedure, and now an NIH sponsored clinical trial is being conducted to further study lumbar to sacral nerve rerouting in spina bifida patients. In addition, similar procedures have been done worldwide, with Dr. Xiao helping to mentor the surgeons at each site.

The Chinese people and government should be proud of Dr. Xiao for his dedication to his patients, his scientific achievements, and his willingness to train doctors around the world how to perform his surgery. The International scientific community was shocked to hear of Dr. Xiao’s arrest. Those of us who know Dr. Xiao well find it difficult to believe that he is involved in these attacks.

Dr. Xiao is a compassionate man who is respected worldwide for his integrity and his innovative scientific contributions to society. We implore the Chinese government and authorities to treat Dr. Xiao fairly and to protect his human rights as these charges are investigated. Please strongly consider Dr. Xiao’s scientific and humanitarian contributions to the world as facts are gathered in this case.

Sincerely,

Kenneth M. Peters, MD
Professor and Chairman of Urology
Beaumont Hospital
Royal Oak, Michigan USA

Jack S. Elder, M.D.
Chief of Urology, Henry Ford Health System
Associate Director, Vattikuti Urology Institute
Department of Urology,
Children's Hospital of Michigan
Detroit, MI USA

Edwin A. Smith M.D.
Assistant Clinical Professor of Urology
Emory University School of Medicine
Atlanta, Georgia USA

Kevin M. Feber, MD, FAAP
Beaumont Children's Hospital
Royal Oak, MI USA

Ananias C. Diokno, M.D., F.A.C.S.
Executive Vice President & CMO
Beaumont Hospital
Royal Oak, Michigan 48073 USA

Juan José de Benito
Urologist
Hospital Nacional de Clínicas
Córdoba, Argentina.

William E. Nantau B.Sc., CNIM
Clinical Manager
Clinical Neurophysiology Department
Beaumont Hospital Royal Oak, MI USA

Evan J Kass MD,FACS,FAAP
Chief, Division of Pediatric Urology
Beaumont Childrens Hospital

Professor of Urology, Oakland University-William
Beaumont School of Medicine
USA

Jacques Corcos MD.
Professor of Urology, McGill University
General Secretary of the International Continence
Society
Jewish General hospital
3755 Cote Ste-Catherine
Montreal, Quebec, Canada H3T 1E2

Jose Gonzalez, M.D.
Department of Urology
Beaumont Hospital
Royal Oak, Michigan USA

Christopher Payne, MD
Associate Professor of Urology
Stanford University Medical School
Stanford, CA 94305-5118 USA

Kenneth I. Glassberg, MD
Director, Division of Pediatric Urology
Morgan Stanley Children's Hospital of New York-
Presbyterian

Professor of Urology, Columbia University
College of Physicians and Surgeons
3959 Broadway, CHN 1118 NY USA

Earl Y. Cheng, MD
Associate Professor of Urology
Children’s Memorial Hospital
Chicago, Illinois USA

Darius J. Bagli, MDCM
Professor of Surgery
Senior Associate Scientist
Director of Urology Research
Divisions of Urology and
Developmental & Stem Cell Biology
The Hospital For Sick Children
Institute of Medical Science
University of Toronto

Henri B. LOTTMANN, MD, FEBU, FEBPS,
FRCS(england) FEBPU
Paediatric urology unit
Hopital Necker-Enfants-Malades
149, rue de Sèvres
75015 Paris, France

Dr. Amrish Vaidya MS. MCh.
Consultant Paediatric Surgeon,
Kokilaben Dhirubhai Ambani Hospital,
4 Bungalows, Andheri W, Mumbai, India

Marc Cendron, MD
Associate Professor in Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA USA

Stuart B. Bauer, MD
Associate Director, Neurourology
Professor of Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA USA

Edmond T. Gonzales, Jr., MD
Professor of Urology
Baylor College of Medicine
Houston TX USA

Richard Macchia, MD FACS
SUNY Distinguished Teaching Professor
Cleveland Clinic, Florida

Benjamin Girdler, MD
Urology Center of the Rockies
Fort Collins, Colorado USA

William C. de Groat, Ph.D.
Professor of Pharmacology
University of Pittsburgh
Pittsburgh, PA USA

Michael R. Ruggieri, Sr., Ph.D.
Director of Urologic Research
Temple University School of Medicine
Philadelphia, PA USA

Stanley J Kogan MD
Chief, Pediatric Urology
Children's Hospital at Montefiore
Bronx NY USA

Anthony Caldamone, MD
University Urologic Associates, Inc.
2 Dudley St Ste 185
Providence, RI 02905 USA

Yves Homsy MD, FRCSC, FAAP
Clinical Professor of Urological Surgery and
Pediatrics
University of South Florida
Children's Urology Group
5507 E. Longboat Blvd
Tampa FL 33615 USA

Dr. Enrique Turina
Professor of urology of the National University of
Buenos Aires
Chief of section Urology of Instituto de
Rehabilitación
Government of Buenos Aires, Argentina.

Dr. Angel Ozón
Urologist of the Instituto de Rehabilitación of Buenos
Aires

Dr. Daniel Ekizian
Urologist of Instituto de Rehabilitación.
Professor Dr. med. Karl-Dietrich Sievert
Vice Chair

Prof. of Urology, Director - Uro-oncology,
Neurourology, Incontinence, & Reconstructive
Urology
Department of Urology University of Tuebingen
D72076 Tuebingen, Germany

Holly Gilmer, MD
Chief of Pediatric Neurosurgery
Beaumont Hospital
Royal Oak, Michigan USA

Yegappan Lakshmanan, MD
Chief, Pediatric Urology
Children’s Hospital of Michigan
Detroit, MI USA

Wednesday, September 29, 2010

Nature: Brawl in Beijing

The following is a news report by Nature on September 29, 2010.

The story incorrectly identified this blog as Dr. Fang Shimin's web site. The correct web site is at http://www.xys.org and is in Chinese. Dr. Fang is not personally involved in this blog.

Brawl in Beijing
Critics of Chinese researchers targeted in physical attacks

David cyranoski

Science can be a rough game in China. On 29 August, on his way home from a tea house in Beijing, Fang Shimin was assaulted. The former biochemist — who for the past decade has run a website exposing scientific fraudsters — was chased by two men, caught and attacked with a hammer.

"I believe they planned to kill me," he says. "The only way to shut me up is to kill me." He escaped with only minor cuts and bruises. In June, Fang Xuanchang, a journalist who had reported on corruption in science in China, was left with more serious injuries after two men assaulted him with steel rods.

On 21 September, police arrested Xiao Chuanguo, a urologist at Tongji Medical College in Wuhan, on suspicion of master minding both plots. Xiao could not be reached for comment, but has confessed his involvement to Beijing's police. Fang Shimin says Xiao could face 3–10 years in prison — or more if the charges become attempted murder.

Xiao and Fang Shimin have never met or spoken, but their paths have crossed on the Internet — and in court. Xiao's clash with him, and with Fang Xuanchang, revolves around a surgical procedure devised by Xiao that aims to restore bladder and bowel function in patients with spina bifida or spinal-cord injuries. Xiao reported an impressive 87% success rate for the operation, which involves re-routing nerves[1,2]. In 2005, he was nominated for membership of the Chinese Academy of Sciences, the elite body of the Chinese scientific world.

Following his nomination, people started posting questions about Xiao's claims on Fang Shimin's website (http://fangzhouzi-xys.blogspot.com). Then in September 2005, Fang Shimin published an essay in Beijing Sci–Tech Report, which said that Xiao was not an associate professor at New York University as he states in his CV, but only an assistant professor. Furthermore, the article said that only 4 of the 26 English-language publications Xiao listed were journal articles — the rest being abstracts from conference proceedings.

It is not known if Fang Shimin's article affected the academy's decision, but Xiao was not made a member and has since sued Fang Shimin for libel five times. Fang Shimin, whose site has been criticized for giving contributors a platform for unjustified attacks on their enemies[3], lost one case and won two, with the other two undecided. Meanwhile, criticism of the 'Xiao procedure' has continued. Last year, Fang Xuanchang published a series of articles questioning its efficacy, which may have prompted the attacks on him.

Beijing-based lawyer Peng Jian says he has interviewed 20–30 patients who have experienced side effects after undergoing the Xiao procedure, and who are seeking compensation. This summer, the first US trial of the treatment reported ambiguous results in The Journal of Urology[4], and two journal editorials said it should be considered experimental[4].

Fang Shimin, meanwhile, is unfazed by the attack. "It won't stop me," he says. "I will continue to do what I am doing."

References
1. Xiao, C.-G. Proc. Int. Conf. Urol. Shanghai, 2–4 July (2005).
2. Xiao, C.-G. Eur. Urol. 49, 22-29 (2006).
3. Cyranoski, D. Nature 441, 392-393 (2006).
4. Peters, K. M. et al. J. Urol. 184, 702-708 (2010).

Monday, September 27, 2010

Xiao Chuanguo vs. Fang Zhouzi: A Chronology

Professor Xiao Chuanguo first surfaced in the world internet forums some time near the turn of the centry. But nobody knew him then -- He was posting under a pseudonym "Confused Professor" (昏教授). Around the same time, Fang Zhouzi was starting his efforts in exposing scientific fraud in China. "Confused Professor" took an interest in Fang Zhouzi's actions and decided that he didn't like what he saw. He posted a few articles criticizing Fang Zhouzi.

In 2001, Fang Zhouzi published a popular science essay in a newspaper in China, introducing some recent research results to the general public. "Confused Professor" reported it to Science, which carried the original study, as a case of plagiarism. Science responded that it was not plagiarism because Fang Zhouzi "neither implied that the work was his own by writing in the first person nor directly copied the language in the Science paper." Nevertheless, "Confused Professor" and his followers continued to propagate the myth that Fang Zhouzi had committed plagiarism.

Fast forward to the fall of 2005, "Confused Professor" was revealed to be Professor Xiao Chuanguo, then in the process of moving back to China from his post in New York and applying to become a member of the prestigeous Chinese Academy of Science. Alerted netters wrote to New Threads suggesting that Xiao Chuanguo had been mispresenting his resume in his application. On September 21, 2005, Fang Zhouzi publised an essay in Beijing Science and Technology summarizing the charges, questioning Xiao Chuanguo's claims of his academic status, number of publications and that he had invented a world-famous "Xiao's Procedure" (At that time, the term "Xiao's Procedure" had only existed in Xiao Chuanguo's own tellings).

In October, Xiao Chuanguo sued Fang Zhouzi and the newspapers that carried the articles.

May, 2006, as Fang Zhouzi's efforts were exposing more scientific fraud in China, 120 Chinese scholars, mostly biologists based in US, published an open letter calling for a stop of such public investigation in the name of protecting scientists' reputations.

That June, Xiao Chuanguo also published an open letter of his own, attacking Fang Zhouzi personally and swore that "this must be revenged!" He followed that up by launching a series of libel suits against Fang Zhouzi.

On July 31, 2006, a local court in Wuhan reached verdict on the very first Xiao Chuanguo vs. Fang Zhouzi case. The court decided in favor of Xiao Chuanguo, employing some very convoluted logic. Fang Zhouzi denounced it as a practice of local protectionism and vowed to defy any penalty ruling.

That very same day, an open letter supporting Fang Zhouzi began circulating. Over a hundred people signed up right away. The number of signatures eventually reached over 600.

September 5, 2006, Xiao Chuanguo launched another lawsuit against Fang Zhouzi, this time in Beijing, challenging Fang Zhouzi's assertion of local protectionism in Wuhan, where Xiao Chuanguo lived and worked. Also in that September, Rao Yi, then a professor at Northwestern University in US, published a friend-of-court style essay criticizing Xiao Chuanguo. In China, Professor Qing Chenrui (the wife of Professor He Zuoxiu) also published an open letter supporting Fang Zhouzi.

By November that year, escalation continued. Xiao Chuanguo launched another round of lawsuits, this time in New York against Rao Yi, Fang Zhouzi, and New Threads. (Rao Yi's insurance company in US eventually settled on his behalf.)

In China, Professor He Zuoxiu and Fang Zhouzi's lawyer Peng Jian established a Fund in support Fang Zhouzi, who at that time was also facing several other lawsuits in addition to those by Xiao Chuanguo. Overseas, The Organization of Scientific and Academic Integrity in China was also formed to collect donations supporting Fang Zhouzi's cause. Science reported thusly, "China's Fraud Buster Hit by Libel Judgements; Defenders Rally Round"

March, 2007, Xiao Chuanguo, together with other plaintiffs against Fang Zhouzi, issued a public threat to all signatories of the open letter supporing Fang Zhouzi, vowing to sue every person who did not publicly rennounce their signatures. Within that month, Fang Zhouzi lost most of those cases in several courts. He once again pledged to defy the judgements.

But then on May 28, 2007, Beijing Intermediate Court reached a verdict in Fang Zhouzi's favor, a first court victory of its kind.

After that, the dispute seems to have died down for a couple of years until August 2009 when Xiao Chuanguo boasted on Internet that he had received a court-issued fine from Fang Zhouzi. It was news to the latter. It was then that Fang Zhouzi discovered that his wife's bank account had been raided by the Wuhan court without their knowledge. (Fang Zhouzi and his wife had a prenuptial agreement that separates their finances.) His appeal was denied by the court.

In the months of October through December of 2009, a couple of Chinese newspapers, led by science reporter Fang Xuanchang, published a series of investigative findings exposing the ineffectiveness of the Xiao's Procedure and its severe side effects. Lawyer Peng Jian announced lawsuits to seek damages from the surgery.

February, 2010, A group of volunteers of New Threads collected documented materials and published an open letter questioning the Xiao's Procedure. The letter was sent to several institions and hospitals involved in clinical trials of the procedure in US.

August, 2010, the first clinial trial result of Xiao's Procedure from Beaumont Hospital in Michigan, US, was published in Journal of Urology. The journal also published sharply critical comments.

June 24, 2010, reporter Fang Xuanchang was brutally attacked by two thugs on his way home. He suffered serious head injuries and barely escaped.

August 29, 2010, Fang Zhouzi was attacked in daylight in a similar mannar. Fortunately he was able to escape with only minor injuries.

September 20, 2010, Xiao Chuanguo was arrested and identified as the mastermind behind both attacks.


Friday, September 24, 2010

More Retractions from Nobel Laureate Linda Buck

After retracting an influential paper from Nature a year and half ago, Nobel laureate Linda Buck is now retracting two more papers from Science and PNAS, respectively, as they have failed to reproduce the findings in these papers. All three papers were first-authored by Zou Zhihua (邹志华), a Chinese researcher who worked as a postdoc for Buck from 1997 to 2005.

In 2008, Zou wrote in a statement provided by UTMB [University of Texas Medical Branch] that he was "disappointed" by the Nature retraction, he "declined to sign" the Science retraction, as reported online today in Science. But "we have no information to suspect misconduct," Natasha Pinol, senior communications officer at the AAAS/Science Office of Public Programs, told The Scientist in an email.

In addition to the irreproducible results, the PNAS paper also contained "figures inconsistent with original data," according to the FHCRC statement. While the PNAS retraction is "not embargoed," according to Managing Editor Daniel Salsbury, the journal refused to share any information with The Scientist.

Zou Zhihua is reported to be currently in China and unavailable to comment.

Thursday, September 23, 2010

Science: Urologist Arrested for Attacks on Chinese Whistleblowers

The following is a report by Science on September 23, 2010.

Urologist Arrested for Attacks on Chinese Whistleblowers
by Hao Xin

BEIJING—The police bureau here announced Tuesday evening that they have detained the suspected mastermind behind assaults on China's science misconduct watchdog Fang Shimin (aka Fang Zhouzi) and journalist Fang Xuanchang. (The two Fangs are not related.)

Earlier on 21 September, police detained Xiao Chuanguo, chief urology surgeon at the Tongji Hospital affiliated with Huazhong University of Science and Technology (HUST) in Wuhan, after Xiao returned from a trip to Argentina. According to a Beijing police report published online, Xiao believed that the Fangs' muckraking investigation of his academic achievements resulted in his failure to be elected a member of the Chinese Academy of Sciences (CAS). Chinese media have reported that, according to a police briefing, Xiao paid about $15,000 to a distant relative, who allegedly arranged the assaults on Fang Xuanchang in June and Fang Zhouzi in August. Police took the relative and two accomplices into custody earlier this month.

The bone of contention between Xiao and the Fangs is a surgical procedure Xiao developed that he claimed can help patients with spinal cord injury and spina bifida to restore some control over bladder and bowl movements. After seeing material supporting Xiao's nomination as member of CAS in 2005, Fang Zhouzi asserted on his Web site, New Threads, that Xiao's procedure was not nearly as internationally famous as Xiao claimed and alleged that Xiao exploited the Chinese public's inability to access information in English to inflate his achievement. Xiao sued Fang for libel in a Wuhan court and won in 2006, but attempts to sue Fang in Beijing courts failed.

Last December, while working for the biweekly Chinese Science News, Fang Xuanchang edited a series of investigative reports on Xiao's procedure, which has been performed on thousands of Chinese patients, according to Xiao. Before the Ministry of Health in May 2009 issued regulations banning the clinical application of unproven and controversial medical procedures such as stem cell therapy, some Chinese hospitals peddled experimental procedures to make more money. It's not clear whether Xiao's procedure falls in the banned category, but no clinical trials have been conducted in China to prove its efficacy. Many prospective patients were enticed by the touted 85% success rate. Since publication of the investigative reports, however, "the number of patients seeking treatment has fallen sharply," says Jia Hepeng, editor-in-chief of Chinese Science News.

The procedure also caught the attention of Kenneth Peters, director of urology research at the William Beaumont Hospital in Royal Oak, Michigan, who launched a phase II clinical trial at his hospital (see also an Associated Press report). Trial results have not been published. Peters also obtained two grants from the National Institute of Health to study the safety and efficacy of the procedure for treating spina bifida patients. According to a description in his grant proposal, preliminary results show that seven out of nine patients who received the treatment have shown improvements. Peters did not respond to an e-mail request for comment.

Xiao could not be reached for comment. His employer, HUST, yesterday issued an online statement that said the university was shocked by the police investigation into Xiao's alleged crime of intentional injury to others. The statement says that the university will follow the case closely and take appropriate action once the judicial system renders its verdict.

Wednesday, September 22, 2010

Details of the Fang Zhouzi Attack Emerging

A day after the Beijing police arrested Xiao Chuanguo, a few details of the case and its investigation started to emerge publicly.

After the attack on Fang Zhouzi gained much publicity, both local and city police allocated a large amount of resources to investigate the case. They interviewed close to a thousand people in the area and identified a couple of eyewitnesses. They were also able to retrieve a surveillance video footage showing a man following Fang Zhouzi right before the attack.

Within days from the attack, police was already able to identify the man in the video as 32-year-old Xu Lichun (许立春). Further surveillance on Xu Lichun then led police to his co-suspect Long Guangxing (龙光兴) and Dai Jianxiang (戴建湘). After they were comprehended, Dai Jianxiang, a distant relative of Xiao Chuanguo's, confessed that Xiao Chuanguo paid him 100,000 RMB (14,000 USD) to "teach Fang Zhouzi and Fang Xuanchang a lesson". Dai Jianxiang then offered half of that money to Xu Lichun and Long Guangxing to do the dirty work.

Xiao Chuanguo himself was abroad at the time of these arrests, so the crack of the case was kept secret for days, until police was able to arrest Xiao Chuanguo on his return at the Shanghai Airport yesterday.

The attack itself was more dangerous than it had previous thought. Fang Zhouzi escaped thanks in part to a comical error committed by the perpetrators. The attack was designed to have Xu Lichun confront Fang Zhouzi head on with pepper juice and an iron hammer while Long Guangxing hit with a steel rod behind Fang Zhouzi's back at the same time. Fortunately, Fang Zhouzi ducked quickly enough that the majority of the pepper juice landed on Long Guangxing's face instead, neutralizing that sneak attack. Fang Zhouzi was then able to run away. Xu Lichun chased and threw his hammer to him a couple of times. He managed to hit Fang Zhouzi on the back once but only caused minor injuries.

Various news reports indicate that all suspects, including the mastermind Xiao Chuanguo himself, had already confessed their criminal actions to police.