Open letter in support of Chuan-Guo Xiao, M.D. from theInternational Academic CommunitySeptember 29, 2010To all,We have all had the pleasure of knowing Dr. Chuan-Guo Xiao for many years. He is an internationally respected surgeon-scientist who has made major advances in the development of neuroregeneration to restore voiding and bowel function. Dr. Xiao performed groundbreaking animal research in the United States, demonstrating that a motor nerve that innervates the leg can be used to reinnervate the bladder and bowel. This reinnervation allows for development of a reflex to initiate bladder function. The results of his studies were published in peer-reviewed journals and other scientists have replicated Xiao’s findings confirming these results.Dr. Xiao eventually took the courageous step of moving from animal research to human studies and began performing the rerouting procedure on patients with spinal cord injury and spina bifida in China. Neurogenic bladder is life threatening in China due to a lack of both antimuscarinics and intermittent catheterization, and lessening the complications of neurogenic bladder would be considered a lifesaving success. Patients with neurogenic bladder and bowel suffer greatly and endure a host of issues such as urinary retention, incontinence, recurrent infections, renal insufficiency, fecal incontinence, constipation, and poor quality of life. For a procedure as complicated as nerve rerouting requiring nerve regeneration, one cannot expect normalization of bladder and bowel function to be the definition of success. What is important is that the benefits outweigh the risks of the procedure.Dr. Xiao published his clinical results in peer-reviewed journals and was twice honored by the Jack Lapides Essay Contest, one of the most respected international awards given to scientists who make major contributions to the field of neurourology. In 2008, he was named the Kelm Hjalmas Memorial Lecturer from the International Children’s Continence Society for his scientific achievements. Many of us have traveled to China to examine patients treated by Dr. Xiao and/or have been trained by him in the nerve rerouting surgery he invented. Dr. Xiao is a very skilled surgeon who is passionate about patient care and works tirelessly to train physicians around the world in performing his nerve rerouting procedure.In the United States, an independent and very rigorous pilot research trial was performed to test the safety and efficacy of this procedure. The one-year results were recently published in the Journal of Urology. At the 12-month follow-up visit, a cutaneous to bladder reflex was found in 7 of 9 spina bifida patients, confirming that rerouting does occur. This finding by itself is remarkable and Dr. Xiao should be commended. In addition, a number of patients demonstrated improvement in bladder and bowel function, which has continued to improve with longer patient follow-up.The 36-month results are currently being analyzed and will be reported in the near future. The pilot data was supportive of Dr. Xiao’s procedure, and now an NIH sponsored clinical trial is being conducted to further study lumbar to sacral nerve rerouting in spina bifida patients. In addition, similar procedures have been done worldwide, with Dr. Xiao helping to mentor the surgeons at each site.The Chinese people and government should be proud of Dr. Xiao for his dedication to his patients, his scientific achievements, and his willingness to train doctors around the world how to perform his surgery. The International scientific community was shocked to hear of Dr. Xiao’s arrest. Those of us who know Dr. Xiao well find it difficult to believe that he is involved in these attacks.Dr. Xiao is a compassionate man who is respected worldwide for his integrity and his innovative scientific contributions to society. We implore the Chinese government and authorities to treat Dr. Xiao fairly and to protect his human rights as these charges are investigated. Please strongly consider Dr. Xiao’s scientific and humanitarian contributions to the world as facts are gathered in this case.Sincerely,Kenneth M. Peters, MDProfessor and Chairman of UrologyBeaumont HospitalRoyal Oak, Michigan USAJack S. Elder, M.D.Chief of Urology, Henry Ford Health SystemAssociate Director, Vattikuti Urology InstituteDepartment of Urology,Children's Hospital of MichiganDetroit, MI USAEdwin A. Smith M.D.Assistant Clinical Professor of UrologyEmory University School of MedicineAtlanta, Georgia USAKevin M. Feber, MD, FAAPBeaumont Children's HospitalRoyal Oak, MI USAAnanias C. Diokno, M.D., F.A.C.S.Executive Vice President & CMOBeaumont HospitalRoyal Oak, Michigan 48073 USAJuan José de BenitoUrologistHospital Nacional de ClínicasCórdoba, Argentina.William E. Nantau B.Sc., CNIMClinical ManagerClinical Neurophysiology DepartmentBeaumont Hospital Royal Oak, MI USAEvan J Kass MD,FACS,FAAPChief, Division of Pediatric UrologyBeaumont Childrens HospitalProfessor of Urology, Oakland University-WilliamBeaumont School of MedicineUSAJacques Corcos MD.Professor of Urology, McGill UniversityGeneral Secretary of the International ContinenceSocietyJewish General hospital3755 Cote Ste-CatherineMontreal, Quebec, Canada H3T 1E2Jose Gonzalez, M.D.Department of UrologyBeaumont HospitalRoyal Oak, Michigan USAChristopher Payne, MDAssociate Professor of UrologyStanford University Medical SchoolStanford, CA 94305-5118 USAKenneth I. Glassberg, MDDirector, Division of Pediatric UrologyMorgan Stanley Children's Hospital of New York-PresbyterianProfessor of Urology, Columbia UniversityCollege of Physicians and Surgeons3959 Broadway, CHN 1118 NY USAEarl Y. Cheng, MDAssociate Professor of UrologyChildren’s Memorial HospitalChicago, Illinois USADarius J. Bagli, MDCMProfessor of SurgerySenior Associate ScientistDirector of Urology ResearchDivisions of Urology andDevelopmental & Stem Cell BiologyThe Hospital For Sick ChildrenInstitute of Medical ScienceUniversity of TorontoHenri B. LOTTMANN, MD, FEBU, FEBPS,FRCS(england) FEBPUPaediatric urology unitHopital Necker-Enfants-Malades149, rue de Sèvres75015 Paris, FranceDr. Amrish Vaidya MS. MCh.Consultant Paediatric Surgeon,Kokilaben Dhirubhai Ambani Hospital,4 Bungalows, Andheri W, Mumbai, IndiaMarc Cendron, MDAssociate Professor in UrologyHarvard Medical SchoolChildren’s Hospital BostonBoston, MA USAStuart B. Bauer, MDAssociate Director, NeurourologyProfessor of UrologyHarvard Medical SchoolChildren’s Hospital BostonBoston, MA USAEdmond T. Gonzales, Jr., MDProfessor of UrologyBaylor College of MedicineHouston TX USARichard Macchia, MD FACSSUNY Distinguished Teaching ProfessorCleveland Clinic, FloridaBenjamin Girdler, MDUrology Center of the RockiesFort Collins, Colorado USAWilliam C. de Groat, Ph.D.Professor of PharmacologyUniversity of PittsburghPittsburgh, PA USAMichael R. Ruggieri, Sr., Ph.D.Director of Urologic ResearchTemple University School of MedicinePhiladelphia, PA USAStanley J Kogan MDChief, Pediatric UrologyChildren's Hospital at MontefioreBronx NY USAAnthony Caldamone, MDUniversity Urologic Associates, Inc.2 Dudley St Ste 185Providence, RI 02905 USAYves Homsy MD, FRCSC, FAAPClinical Professor of Urological Surgery andPediatricsUniversity of South FloridaChildren's Urology Group5507 E. Longboat BlvdTampa FL 33615 USADr. Enrique TurinaProfessor of urology of the National University ofBuenos AiresChief of section Urology of Instituto deRehabilitaciónGovernment of Buenos Aires, Argentina.Dr. Angel OzónUrologist of the Instituto de Rehabilitación of BuenosAiresDr. Daniel EkizianUrologist of Instituto de Rehabilitación.Professor Dr. med. Karl-Dietrich SievertVice ChairProf. of Urology, Director - Uro-oncology,Neurourology, Incontinence, & ReconstructiveUrologyDepartment of Urology University of TuebingenD72076 Tuebingen, GermanyHolly Gilmer, MDChief of Pediatric NeurosurgeryBeaumont HospitalRoyal Oak, Michigan USAYegappan Lakshmanan, MDChief, Pediatric UrologyChildren’s Hospital of MichiganDetroit, MI USA
Thursday, September 30, 2010
International Scholars Issue Open Letter Supporting Xiao Chuanguo
Exactly one year ago, Hollywood celebrities were busy writing appealing letters on behalf of Roman Polanski, a movie director who was convicted for child rape. A couple of years earlier, a world-renowned scientist, William French Anderson, might have his sentence for molestation reduced because of supporting letters from his colleagues, including a Nobel Laureate.
Today, 31 internationally-renowned scholars, most of whom are accepting fundings for experiments on Xiao's Procedure, issued an open letter supporting Dr. Xiao Chuanguo, who had confessed to the hideous crime of masterminding two brutal attacks on an investigative reporter and a free-lance writer who had worked to expose his fraud.
The common thread of these letters is that their authors pay little or no regards to the horrible injuries caused by the perpetrators, in the name that the criminals or suspects had previous made valuable contributions to the society and therefore somehow should be judged more than mere citizens. Where are the moral standards?
In addition, this particular letter once again states the Beaumont Hospital result has confirmed that "[nerve] rerouting does occur," without even a mention of the critical comments by their peers published in the same issue of the Journal of Urology. Where is scholastic honesty?
To those protected elites who never fail to protect one of their own, where is the shame?
Below is the open letter, in its entire glory: